Perioral Dermatitis Causes & Treatment | Charlotte Dermatology Blog
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blog

All About Perioral Dermatitis

April 23rd, 2025 | By: Admin

Perioral dermatitis is a common rash around the mouth that can cause redness, burning, flaking and small pustules and is often mistaken for acne. Common variations are perinatal (around the nose) and periocular (around the eyes) dermatitis.


What is the Cause of Perioral Dermatitis?

The cause is not known, but there is some belief that steroids, whether topical, nasal or inhaled can be a trigger. Once topical steroids are discontinued, the rash may worsen prior to improving. Fluoride toothpastes are also commonly thought to exacerbate the rash.


Treatment for Perioral Dermatitis

Typically, a topical medication known as metronidazole and a common antibiotic called minocycline can treat this common rash. Other antibiotics that are effective include tetracycline, doxycycline and erythromycin. The typical course of treatment is 1-2 months. Follow up occurs at one month and if the rash is better, but not resolved, one more month is required.


Avoidance of topical steroids is essential as this can make the rash worse. Trying Sensodyne toothpaste is often helpful.


Gentle cleansers such as CeraVe, Cetaphil or Vanicream will help minimize the irritation and rash.


This is a common form of dermatitis that can be easily diagnosed by your healthcare provider. If you think you may be suffering from perioral dermatitis, come see us in one of our Charlotte, NC or Myrtle Beach, SC offices so we can help get your skin looking better!


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