What is it?
Photodynamic
Therapy (PDT) is a non-invasive dermatologic treatment that uses a
photosensitizing agent activated by a specific light source to destroy abnormal
or damaged skin cells. It is commonly used to treat actinic keratoses,
early-stage superficial skin cancers, moderate to severe acne, and photoaging.
The treatment works by applying a topical
medication—typically aminolevulinic acid (ALA)—which is absorbed by targeted
cells. After a period of incubation, the treated area is exposed to a
specialized blue or red light, which activates the medication. This process
creates a reaction that destroys the problematic cells while preserving
surrounding healthy skin. PDT can be applied to the face, scalp, chest, and
extremities, depending on the condition being treated.
What to expect
Treatment
begins with a thorough skin evaluation to determine whether PDT is appropriate
for the patient’s condition and skin type. During the procedure, the
photosensitizing agent is applied and allowed to incubate—usually for 1 to 3
hours. After this period, the treated skin is exposed to light, which activates
the medication.
The procedure
typically takes 30–60 minutes and may cause temporary redness, burning, or
peeling—similar to a sunburn. Most patients return to normal activity within
24–48 hours but must avoid sunlight for at least 48 hours post-treatment to
prevent additional photosensitivity. Multiple sessions may be needed depending
on severity and treatment goals.
At Charlotte Dermatology, PDT is offered as part
of comprehensive care for patients with precancerous lesions, persistent acne,
or sun-damaged skin. Providers tailor the treatment plan based on patient
comfort, clinical need, and long-term skin health.
PHOTODYNAMIC THERAPY (PDT) CAN HELP WITH THESE CONDITIONS:
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